T-Lymphocytes Subsets in Patients with chronic hepatitis that showed autoimmune phenomenon

Authors

  • Dhuha S Salih Department of Biology, College of Science, University of Baghdad, Baghdad, Iraq. Author
    • Ayaid K Zqair Department of Biology, College of Science, University of Baghdad, Baghdad, Iraq. Author
      • Ramzia MH AL- Khyat Central Public Health Laboratories, Baghdad, Iraq.Salih DS, et al. (2013) World Journal of Experimental Biosciences. Vol. 1, No.1, 10-13. Author

        Keywords:

        autoimmunity, CD4+ Cells, CD8+ cells, T lymphocytes

        Abstract

        This study included 7 patients with autoimmune chronic hepatitis that infected previously with HBV (AIH-HBV), and 16 healthy human as a control group. No significant difference in number and percentage of T- Lymphocyte (CD3+ Cells) in the peripheral blood of patients with AICH as compared with control group. In addition, no significant increase in the percentage and number of CD4+ cells (P < 0.001) was reported and no significant decrease in the number and percentage of CD8+ cells (P < 0.01) was observed. These finding was concomitant with increase in CD4+/CD8+ ratio as compared with healthy control. In present study, it can conclude that the collaboration activity of both cells (CD4+ and CD8+) plays the crucial role in severity of AIH-HBV.

        Author Biography

        • Ayaid K Zqair, Department of Biology, College of Science, University of Baghdad, Baghdad, Iraq.

          This study included 7 patients with autoimmune chronic hepatitis that infected previously with HBV (AIH-HBV), and 16 healthy human as a control group. No significant difference in number and percentage of T- Lymphocyte (CD3+ Cells) in the peripheral blood of patients with AICH as compared with control group. In addition, no significant increase in the percentage and number of CD4+ cells (P < 0.001) was reported and no significant decrease in the number and percentage of CD8+ cells (P < 0.01) was observed. These finding was concomitant with increase in CD4+/CD8+ ratio as compared with healthy control. In present study, it can conclude that the collaboration activity of both cells (CD4+ and CD8+) plays the crucial role in severity of AIH-HBV.

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        Published

        2013-04-08

        Issue

        Volume 1, Number 1 (2013)

        Section

        Research article

        License

        All articles in the World Journal of Experimental Biosciences are published under the terms of the Creative Commons  Attribution 4.0 International License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 

        How to Cite

        [1]
        Dhuha S Salih et al. trans. 2013. T-Lymphocytes Subsets in Patients with chronic hepatitis that showed autoimmune phenomenon. World Journal of Experimental Biosciences. 1, 1 (Apr. 2013), 10–13.

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